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Table 1 Representative genes differentially expressed in CAFs from NGFs

From: FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells

Accession No.

Symbol

Gene name

Fold change

Up-regulated

   

NM_014333

CADM1

Cell adhesion molecule 1, transcript variant 1

273.6

CB178477

XLOC_l2_007424

gb|is39c09.y1 HR85 islet Homo sapiens cDNA clone IMAGE:6554705 5′, mRNA sequence

254.8

NM_001113207

TSTD1

Thiosulfate sulfurtransferase (rhodanese)-like domain containing 1, transcript variant 1

237.5

NM_000867

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B

171.5

NM_001008539

SLC7A2

Solute carrier family 7 (cationic amino acid transporter, y + system), member 2, transcript variant 2

142.5

NM_002010

FGF9

Fibroblast growth factor 9 (glia-activating factor)

141.1

NM_005559

LAMA1

Laminin, alpha 1

119.0

NM_001040058

SPP1

Secreted phosphoprotein 1, transcript variant 1

116.1

A_24_P247454

A_24_P247454

Unknown

112.6

NM_014398

LAMP3

Lysosomal-associated membrane protein 3

111.3

Down-regulated

   

NM_001141919

XG

Xg blood group (XG), transcript variant 2,

0.0035

NM_175569

XG

Xg blood group (XG), transcript variant 1

0.0044

NM_000609

CXCL12

Chemokine (C-X-C motif) ligand 12 (CXCL12), transcript variant 2

0.0071

NM_014817

TRIL

TLR4 interactor with leucine-rich repeats

0.0099

NM_002839

PTPRD

Protein tyrosine phosphatase, receptor type D, transcript variant 1

0.0138

NR_021485

EGFEM1P

EGF-like and EMI domain containing 1, pseudogene, non-coding RNA

0.0141

NM_198285

WDR86

WD repeat domain 86

0.0145

NM_001164000

MECOM

MDS1 and EVI1 complex locus (MECOM), transcript variant 6

0.0166

NM_004335

BST2

Bone marrow stromal cell antigen 2

0.0168

ENST00000484765

XLOC_002912

Hypothetical LOC100507661 (LOC100507661), miscRNA

0.0172

  1. Fold change values were evaluated as a ratio of normalized CAFs/normalized NGFs.