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Table 1 Clinical characteristics of the patients with nasopharyngeal carcinoma stratified by low and high expression of Talin-1

From: High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma

Characteristic

No. of patients

Expression of talin-1

P-value*

  

Low, n (%)

High, n (%)

 

Age

    

≤45 years

114

87 (76.3)

27 (23.7)

0.09

>45 years

119

79 (66.4)

40 (33.6)

 

Sex

    

Male

169

124 (73.4)

45 (26.6)

0.24

Female

64

42 (65.6)

22 (34.4)

 

WHO type

    

I + II

8

4 (50.0)

4 (50.0)

0.23

III

225

162 (72.0)

63 (28.0)

 

VCA-IgA

    

<1:80

35

27 (77.1)

8(22.9)

0.40

≥1:80

198

139 (70.2)

59(29.8)

 

EA-IgA

    

<1:10

57

42 (73.7)

15 (26.3)

0.64

≥1:10

176

124 (70.5)

52 (29.5)

 

T Stage

    

T1-T2

113

85 (75.2)

28 (24.8)

0.19

T3-T4

120

81 (67.5)

39 (32.5)

 

N Stage

    

N0-N1

143

103 (72.0)

40 (28.0)

0.74

N2-N3

90

63 (70.0)

27 (30.0)

 

TNM stage

    

I-II

72

56 (77.8)

16 (22.2)

0.14

III-IV

161

110 (68.3)

51(31.7)

 

Locoregional failure

Yes

39

23 (59.0)

16 (41.0)

0.06

No

194

143 (73.7)

51 (26.3)

 

Distant metastasis

Yes

51

27 (52.9)

24 (47.1)

0.001

No

182

139 (76.4)

43 (23.6)

 

Death

    

Yes

57

31 (54.4)

26 (45.6)

0.001

No

176

135 (76.7)

41 (23.3)

 
  1. Abbreviations: WHO: World Health Organization; VCA-IgA: viral capsid antigen immunoglobulin A; EA-IgA: early antigen immunoglobulin A. P-values* were calculated using the chi-square test or Fisher’s exact test.