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Table 1 Clinical characteristics of the patients with nasopharyngeal carcinoma stratified by low and high expression of Talin-1

From: High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma

Characteristic No. of patients Expression of talin-1 P-value*
   Low, n (%) High, n (%)  
Age     
≤45 years 114 87 (76.3) 27 (23.7) 0.09
>45 years 119 79 (66.4) 40 (33.6)  
Sex     
Male 169 124 (73.4) 45 (26.6) 0.24
Female 64 42 (65.6) 22 (34.4)  
WHO type     
I + II 8 4 (50.0) 4 (50.0) 0.23
III 225 162 (72.0) 63 (28.0)  
VCA-IgA     
<1:80 35 27 (77.1) 8(22.9) 0.40
≥1:80 198 139 (70.2) 59(29.8)  
EA-IgA     
<1:10 57 42 (73.7) 15 (26.3) 0.64
≥1:10 176 124 (70.5) 52 (29.5)  
T Stage     
T1-T2 113 85 (75.2) 28 (24.8) 0.19
T3-T4 120 81 (67.5) 39 (32.5)  
N Stage     
N0-N1 143 103 (72.0) 40 (28.0) 0.74
N2-N3 90 63 (70.0) 27 (30.0)  
TNM stage     
I-II 72 56 (77.8) 16 (22.2) 0.14
III-IV 161 110 (68.3) 51(31.7)  
Locoregional failure
Yes 39 23 (59.0) 16 (41.0) 0.06
No 194 143 (73.7) 51 (26.3)  
Distant metastasis
Yes 51 27 (52.9) 24 (47.1) 0.001
No 182 139 (76.4) 43 (23.6)  
Death     
Yes 57 31 (54.4) 26 (45.6) 0.001
No 176 135 (76.7) 41 (23.3)  
  1. Abbreviations: WHO: World Health Organization; VCA-IgA: viral capsid antigen immunoglobulin A; EA-IgA: early antigen immunoglobulin A. P-values* were calculated using the chi-square test or Fisher’s exact test.