CLU immunohistochemical analyses. (A) Hematoxylin-Eosin staining of a follicular adenoma. (B) Anti-CLU antibody immunostaining of the same adenoma. (C) Hematoxylin-Eosin staining of a papillary carcinoma with adjacent normal thyroid tissue. (D) Anti-CLU antibody immunostaining of the same carcinoma. (E) Immunoreactive epithelial cells in thyroid carcinomas (K, n = 10) and thyroid adenomas (A, n = 40) samples, respectively.