Table 1 Proteins with differential expression/phosphorylation after AMT in A375m2 cells (Kinexus)
From: PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness
Protein | Phosphosite (human) | Refseq | Fold change |
|---|---|---|---|
IKK alpha | Pan-specific | NP_001269 | 6.7 |
CDK7 | Pan-specific | NP_001790 | 5.2 |
ASK1 (MAP3K5) | Pan-specific | NP_005914 | 3.2 |
STAT1a/b | Pan-specific | NP_009330 | 3.2 |
Catenin beta | Pan-specific | NP_001895 | 2.4 |
MEK6 (MAP2K6) | S207 | NP_002749 | 2.3 |
Erk2 | Pan-specific | NP_002736 | 2.3 |
Cofilin 2 | S3 | NP_068733 | 2.3 |
CASP4 | Pan-specific | NP_001216 | 2.1 |
Hsp90 | Pan-specific | NP_005339 | -26.4 |
JNK1/2/3 | Pan-specific | NP_002741 | -22.6 |
Bid | Pan-specific | NP_001187 | -15.2 |
CDK1 (CDC2) | Pan-specific | NP_001777 | -9.6 |
PERP | Pan-specific | NP_071404 | -8.7 |
Hsc70 | Pan-specific | NP_006588 | -6.1 |
JNK2 | Pan-specific | NP_002744 | -5.2 |
APG1 | Pan-specific | NP_055093 | -5.0 |
PDK1 | Pan-specific | NP_002604 | -4.3 |
HO1 | Pan-specific | NP_002124 | -3.8 |
PLC gamma 1 | Y783 | NP_877963.1 | -3.6 |
CaMK1d | Pan-specific | NP_003647 | -3.5 |
MEK4 (MAP2K4) | Pan-specific | NP_003001 | -3.3 |
PKC alpha | S657 | NP_002728 | -3.2 |
IRAK2 | Pan-specific | NP_001561 | -3.2 |
Mnk2 | Pan-specific | NP_060042 | -3.1 |
p35 | Pan-specific | NP_003876 | -3.0 |
FAK | Y577 | NP_005598 | -3.0 |
BRCA1 | S1497 | NP_009225 | -3.0 |
BRCA1 | S1423 | NP_009225 | -2.9 |
4E-BP1 | T45 | NP_004086 | -2.6 |
Bak | Pan-specific | NP_001179 | -2.5 |
MEK1 (MAP2K1) | T385 | NP_002746 | -2.5 |
MEK5 (MAP2K5) | Pan-specific | NP_660143 | -2.4 |
TrkA | Pan-specific | NP_002520 | -2.4 |
Pax2 | S394 | NP_000269.2 | -2.4 |
STAT3 | Pan-specific | NP_003141 | -2.3 |
MEK7 (MAP2K7) | Pan-specific | NP_005034 | -2.3 |
PKC epsilon | S729 | NP_005391 | -2.3 |
PKBb (Akt2) | Pan-specific | NP_001617 | -2.1 |
GCK | Pan-specific | NP_004570 | -2.1 |
p38a MAPK | Pan-specific | NP_001306 | -2.1 |