Transcriptional changes associated with resistance to inhibitors of epidermal growth factor receptor revealed using metaanalysis

Table 1 EGFR inhibitors-sensitive versus resistant cell lines datasets used in metaanalysis of microarrays

Sr. No	Acc. No.	Platform	Set	S+R	S cell lines	R Cell lines	Cell Type	Pretreatment	Inhibitor
1	GSE34228	Agilent-014850	1	26+26	PC9	PC9GR	Non-Small Cell Lung Cancer	No	Gefitinib
			2	26+26	PC9	PC9GR	Non-Small Cell Lung Cancer	EGF	Gefitinib
			3	26+26	PC9	PC9GR	Non-Small Cell Lung Cancer	IRS	Gefitinib
			4	26+26	PC9	PC9GR	Non-Small Cell Lung Cancer	EGF+IRS	Gefitinib
2	GSE10696	Affy HG_ U133_Plus_2.0	1	3+3	A431	A431GR	A431 cancer cell line	No	Gefitinib
3	GSE38310	Illumina HumanHT-12 V3.0	1	3+3	HCC827	T15-2	Non-Small Cell Lung Cancer	DMSO	Erlotinib
			2	3+3	HCC827	T15-3	Non-Small Cell Lung Cancer	Erlotinib	Erlotinib
			3	3+3	HCC827	ER-3	Non-Small Cell Lung Cancer	DMSO	Erlotinib
			4	3+3	HCC827	ER-3	Non-Small Cell Lung Cancer	Erlotinib	Erlotinib
4	GSE40130	Illumina HumanWG-6 v3.0	1	2+3	HN5	FADU	Head and Neck cancer cell lines	No	Erlotinib
		Illumina HumanHT-12 V4.0	2	2+3	HN5	FADU	Head and Neck cancer cell lines	miR-7	Erlotinib
5	GSE49135	Illumina HumanHT-12 V4.0	1	3+3	HN5	HN5ER	Head and Neck cancer cell lines	No	Erlotinib
6	GSE37699	Affy_HG_U133A_2	1	3+3	NSCLC	NCl-H1975	Non-Small Cell Lung Cancer	No	WZ4002
7	GSE38404	Affy_HG_U133A_2	1	2+6	NSCLC	PFR31, PFR32	Non-Small Cell Lung Cancer	No	PF299804
8	GSE21483	Affy HG_ U133_Plus_2.0	1	3+3	SCC1	1Cc8	Skin cancer cell line	No	Cetuximab
	Total		15	274

ISSN: 1471-2407