Figure 1

MiR-34a, miR-150, and miR-923 in the validation cohort. Beeswarm plots of plasma levels of (A) miR-34, (B) miR-150, and (C) miR-923 in the five sample groups; normal (n = 20), polyp (n = 20), adenoma (n = 20), early stage cancer (stage I/II) (n = 23), and advanced cancer (stage III/IV) (n = 14). Expression levels of the miRNAs (log₁₀ scale at y-axis) are normalised to let-7e. Statistically significant differences between groups were determined using Wilcoxon rank sum tests and are represented as follows; p-value <0.05 = *, p-value <0.01 = **, p-value < 0.001 = ***.