Figure 5

Platelets increase MICs marker levels and ovarian cancer sphere formation. mRNA levels in respect to control of SKOV3 (Panel A) and UCI101 (Panel B) cell co-cultured during 6 hours with platelets (150,000/μL, N = 3). Data is represented as the log of the mean relative to control. Representative images of protein levels of ovarian cancer cell lines after 12 hours of co-culture with platelets (Panel C) with quantification in panel D (N = 3) representative images of ovarian cancer spheroids (spheres) formed by UCI101 cells in the presence and absence of platelets (Panel E), with quantification shown in Panel F (N = 3), right: quantification of the total number of spheres counted *p < 0.05 ; **p < 0.01; ***p < 0.001, student t-test.