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Table 3 Adverse reactions (n = 43)

From: Safety and feasibility of adjuvant chemotherapy with S-1 in Japanese breast cancer patients after primary systemic chemotherapy: a feasibility study

 

Grade

 

1

2

3

4

Total

 

n

n

n

n

n

(%)

Hematological toxicities

      

Neutropenia

7

8

1

0

19

(44.2%)

Leukopenia

5

21

2

0

28

(65.1%)

Thrombocytopenia

13

0

0

0

13

(30.2%)

Anemia (Hb)

11

3

0

0

14

(32.6%)

AST

12

0

0

0

12

(27.9%)

ALT

11

0

0

0

11

(25.6%)

Total bilirubin

7

1

0

0

8

(18.6%)

Creatinine

2

0

0

0

2

(4.6%)

Non-hematological toxicities

      

Anorexia

24

4

0

0

28

(65.1%)

General Fatigue

29

2

0

0

31

(72.1%)

Diarrhea

13

0

2

0

15

(34.9%)

Nausea

12

4

0

0

16

(37.2%)

Stomatitis

15

1

0

0

16

(37.2%)

Pigmentation changes

17

3

0

0

20

(46.5%)

Rash

3

1

0

0

4

(9.3%)