Total | RDI < 85% (n = 72) | RDI ≥ 85% (n = 340) | P valuea | |||||
---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | |||
Gender | Male | 222 | 53.9 | 34 | 47.2 | 188 | 55.3 | 0.212 |
Female | 190 | 46.1 | 38 | 52.8 | 152 | 44.7 | ||
Age | <59 y | 146 | 35.4 | 14 | 19.4 | 132 | 38.8 | <0.001 |
59 - 73 y | 135 | 32.8 | 20 | 27.8 | 115 | 33.8 | ||
>73 y | 131 | 31.8 | 38 | 52.8 | 93 | 27.4 | ||
Comorbidity | none | 161 | 39.1 | 22 | 30.6 | 139 | 40.9 | 0.103 |
at least 1 | 251 | 60.9 | 50 | 69.4 | 201 | 59.1 | ||
Standard International prognostic index (sIPI) | very good | 56 | 13.6 | 5 | 6.9 | 51 | 15 | <0.001 |
good | 217 | 52.7 | 29 | 40.3 | 188 | 55.3 | ||
poor | 122 | 29.6 | 37 | 51.4 | 85 | 25 | ||
missing | 17 | 4.1 | 1 | 1.4 | 16 | 4.7 | ||
LDH | normal | 197 | 47.8 | 27 | 37.5 | 170 | 50 | 0.054 |
elevated | 215 | 52.2 | 45 | 62.5 | 170 | 50 | ||
B signs | absence | 336 | 81.6 | 61 | 84.7 | 275 | 80.9 | 0.445 |
presence | 76 | 18.5 | 11 | 15.3 | 65 | 19.1 | ||
Ann Arbor Stage | I-II | 142 | 34.5 | 15 | 20.8 | 127 | 37.4 | 0.007 |
III-IV | 270 | 65.5 | 57 | 79.2 | 213 | 62.7 | ||
Performance status | PS = 0-1 | 385 | 93.5 | 69 | 95.8 | 316 | 92.9 | 0.598 b |
PS = 2-4 | 27 | 6.6 | 3 | 4.2 | 24 | 7.1 | ||
Regimens | R- CHOP 21 or R-CHVP | 223 | 54.1 | 28 | 38.9 | 195 | 57.4 | <0.001 b |
R- CHOP 14 | 34 | 8.3 | 10 | 13.9 | 24 | 7.1 | ||
R- ACVBP | 45 | 10.9 | 3 | 4.2 | 42 | 12.4 | ||
R-mini CHOP or R-mini CHVP | 100 | 24.3 | 30 | 41.7 | 70 | 20.6 | ||
other | 10 | 2.4 | 1 | 1.4 | 9 | 2.7 |