Serine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer

BMC Cancer

Table 2 Univariate and Multivariate Analyses of STYK1 Expression and Disease-Specific Survival of Patients in the Study Cohort

Variables	Categories	Univariate analysis			Multivariate analysis^b
		HR	95% CI	P value^c	HR	95% CI	P value^c
Age ( years)	≥60 / <60	1.182	0.801-1.745	0.399
Sex	Male / female	1.223	0.878-1.704	0.234
Tumor location	Colon / rectum	1.042	0.745-1.456	0.811
Tumor size (cm)	≥5 / <5	1.266	0.904-1.773	0.170
Differentiation grade	Poor / well + moderate	1.495	1.004-2.227	0.048
TNM stage	III / I+ II	2.262	1.625-3.150	<0.001	2.033	1.455-2.840	<0.001
STYK1 expression^a	High / low	2.340	1.679-3.262	<0.001	2.116	1.513-2.960	<0.001

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.
^a For STYK1, the median value of the IRS was used as the cut-off point for definition of subgroups (low expression and high expression groups).
^b Multivariate models were adjusted for age, sex, tumor location, tumor size, differentiation grade, and TNM stage.
^c Bold type indicates statistical significance.

ISSN: 1471-2407