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Table 3 Clinicopathological features according to BRAF mutations

From: A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer

Characteristics

BRAFWT

BRAFMT

Pvalue

(n= 250,%)

(n= 14,%)

Age

Median (range)

64 (32-86)

64 (46-75)

0.53*

Gender

Male

160 (64.0)

6 (42.9)

0.15**

Primary lesion

Right-sided colon

45 (18.0)

8 (57.1)

0.001**

Left-sided colon

67 (26.8)

3 (21.4)

 

Rectum

138 (55.2)

3 (21.4)

 

Histology

Well, mod

232 (92.8)

8 (57.1)

0.001**

Por, muc

18 (7.2)

6 (42.9)

 

Site of metastasis

Liver

131 (52.4)

6 (42.9)

0.58**

Lung

97 (38.8)

3 (21.4)

0.26**

Lymph node

143 (57.2)

7 (50.0)

0.59**

Peritoneum

45 (18.0)

7 (50.0)

0.009

  1. *Mann–Whitney U test; **χ2 or Fisher exact test.