From: A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer
Gene
Wild type
Mutation type
Mutation rate (%)
KRAS codon 12,13
174
90
34.1
KRAS codon 61, 146
254
10
3.8
NRAS codon 12, 13, 61
253
11
4.2
BRAF codon 600
250
14
5.4
PIK3CA exon 9, 20
247
17
6.4