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Table 2 Effect of the main clinical and pathological parameters on overall survival and progression free survival using multivariate Cox models

From: HNF1B polymorphism influences the prognosis of endometrial cancer patients: a cohort study

 

Overall survival

Progression free survival

Multivariate Cox model

Multivariate Cox model

 

Women

Deaths

HR (95%CI)

Pvalue*

Relapses

HR (95%CI)

Pvalue*

Histotype

191

18

  

22

  

Type I

162

9

1

 

13

1

 

Type II

29

9

2.3 (0.56-9.22)

0.254

9

1.6 (0.51-5.38)

0.406

Myometrial invasion

       

<50%

100

2

1

 

4

1

 

≥50%

91

16

4.4 (0.74-26.07)

0.104

18

3.2 (0.82-12.10)

0.094

FIGO stage

       

I

152

6

1

 

9

1

 

II

12

3

5.9 (1.00-34.54)

0.050

4

5.4 (1.21-23.94)

0.027

III

23

6

6.1 (1.08-34.54)

0.041

6

4.1 (0.75-22.66)

0.102

IV

4

3

7.64 (0.84-69.49)

0.071

3

9.5 (1.16-77.7)

0.036

Adjuvant treatment

       

None

119

6

1

 

10

1

 

Radiotherapy

42

3

0.37 (0.07-1.95)

0.239

2

0.20 (0.04-1.05)

0.057

Chemo-Radiotherapy

30

9

0.94 (0.16-5.58)

0.947

10

0.65 (0.13-3.18)

0.598

rs4430796

       

GG

57

11

1

 

10

1

 

AG + AA

134

7

0.18 (0.06-0.56)

0.003

12

0.46 (0.18-1.13)

0.090

  1. CI = confidence interval, HR = hazard ratio. * P values were calculated with Log-rank test and express statistical differences in overall survival and progression free survival.