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Table 3 Detection of individual high-risk HPV genotypes by CLART and LA in 125 women with ≥ CIN2

From: Comparison of analytical and clinical performance of CLART HPV2 genotyping assay to Linear Array and Hybrid Capture 2: a split-sample study

High-risk genotype

Prevalence

Agreement

CLART, N (%)

LA, N (%)

Relative prevalence CLART vs. LA (95% CI)

CLART+/LA+

CLART+/LA-

CLART-/LA+

CLART-/LA-

Total agreement (95% CI)

Positive agreement (95% CI)

16

55 (44%)

57 (46%)

0.96 (0.73-1.27)

55 (44%)

0 (0%)

2 (2%)

68 (54%)

98% (94-100)

96% (88-100)

18

18 (14%)

18 (14%)

1.00 (0.55-1.83)

18 (14%)

0 (0%)

0 (0%)

107 (86%)

100% (97-100)

100% (81-100)

31

30 (24%)

30 (24%)

1.00 (0.64-1.55)

30 (24%)

0 (0%)

0 (0%)

95 (76%)

100% (97-100)

100% (88-100)

33

21 (17%)

22 (18%)

0.95 (0.55-1.64)

21 (17%)

0 (0%)

1 (1%)

103 (82%)

99% (96-100)

95% (77-100)

35

7 (6%)

6 (5%)

1.17 (0.40-3.37)

6 (5%)

1 (1%)

0 (0%)

118 (94%)

99% (96-100)

86% (42-100)

39

4 (3%)

12 (10%)

0.33 (0.11-1.01)

4 (3%)

0 (0%)

8 (6%)

113 (90%)

94% (88-97)

33% (10-65)

45

6 (5%)

17 (14%)

0.35 (0.14-0.87)

6 (5%)

0 (0%)

11 (9%)

108 (86%)

91% (85-96)

35% (14-62)

51

15 (12%)

17 (14%)

0.88 (0.46-1.69)

15 (12%)

0 (0%)

2 (2%)

108 (86%)

98% (94-100)

88% (64-99)

52

17 (14%)

15 (12%)

1.13 (0.59-2.17)

11 (9%)

6 (5%)

4 (3%)

104 (83%)

92% (86-96)

52% (30-74)

56

6 (5%)

9 (7%)

0.67 (0.24-1.82)

5 (4%)

1 (1%)

4 (3%)

115 (92%)

96% (91-99)

50% (19-81)

58

19 (15%)

10 (8%)

1.90 (0.92-3.92)

10 (8%)

9 (7%)

0 (0%)

106 (85%)

93% (87-97)

53% (29-76)

59

9 (7%)

10 (8%)

0.90 (0.38-2.14)

8 (6%)

1 (1%)

2 (2%)

114 (91%)

98% (93-100)

73% (39-94)

68

7 (6%)

3 (2%)

2.33 (0.62-8.82)

0 (0%)

7 (6%)

3 (2%)

115 (92%)

92% (86-96)

0% (0-31)