Table 1 Clinical and biological features of the CLL patients included in the study
From: MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL
Parameter | Category | |
|---|---|---|
Age (years), median (range) | 66 (34-90) | |
Gender | Male | 66.0% |
White blood cells/mL (range) | 21 545 (7 080-188 020) | |
Lymphocytes/mL (range) | 15 741 (1 580-180 000) | |
Hemoglobin, g/dL (range) | 14.1 (4.4-16.8) | |
Platelet count/mL (range) | 171 500 (23 000-399 000) | |
IGHV | Unmutated | 50.3% |
Binet stage | A | 65.9% |
B | 23.2% | |
C | 10.9% | |
LDH | Normal | 81.6% |
High | 18.4% | |
b2microglobulin | Normal | 55.9% |
High | 44.1% | |
Bone marrow pattern | Diffuse | 41.9% |
Other | 58.1% | |
Hepatomegaly | Yes | 10.5% |
No | 89.5% | |
Splenomegaly | Yes | 26.5% |
No | 73.5% | |
B symptoms | Yes | 13.5% |
No | 86.5% | |
Dead during follow-up | Yes | 21.6% |
No | 78.4% | |
Therapy during follow-up | Yes | 45.7% |
No | 78.4% |