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Table 1 Clinical and biological features of the CLL patients included in the study

From: MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL

Parameter Category  
Age (years), median (range)   66 (34-90)
Gender Male 66.0%
White blood cells/mL (range)   21 545 (7 080-188 020)
Lymphocytes/mL (range)   15 741 (1 580-180 000)
Hemoglobin, g/dL (range)   14.1 (4.4-16.8)
Platelet count/mL (range)   171 500 (23 000-399 000)
IGHV Unmutated 50.3%
Binet stage A 65.9%
B 23.2%
C 10.9%
LDH Normal 81.6%
High 18.4%
b2microglobulin Normal 55.9%
High 44.1%
Bone marrow pattern Diffuse 41.9%
Other 58.1%
Hepatomegaly Yes 10.5%
No 89.5%
Splenomegaly Yes 26.5%
No 73.5%
B symptoms Yes 13.5%
No 86.5%
Dead during follow-up Yes 21.6%
No 78.4%
Therapy during follow-up Yes 45.7%
No 78.4%
  1. Results expressed as median or percentages.
  2. IGHV: immunoglobulin heavy variable gene; LDH: lactate dehydrogenase.