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Table 2 Cox regression analysis for disease-free survival in TNBC

From: Pre-treatment neutrophil to lymphocyte ratio may be a useful tool in predicting survival in early triple negative breast cancer patients

Parameters

Univariate

Multivariate

p-value

HR, 95% CI

p-value

Age (≤50 years vs >50 years)

0.12

2.18 (0.02-143.2)

0.74

Menopausal Status (Pre- vs Post-)

0.15

0.80 (0.01-51.3)

0.91

Tumour size (pT1 vs pT2-T3)

0.08

1.81 (0.45-7.14)

0.39

Lymph node status (pN0 vs pN+)

0.2

1.25 (0.31-4.96)

0.74

Nuclear Grade (G1-G2 vs G3)

0.08

0.66 (0.27-1.62)

0.37

Ki-67 (≤20% vs >20%)

0.38

0.78 (0.27-2.26)

0.66

Lympho-vascular invasion (absence vs presence)

0.17

1.68 (0.26-10.70)

0.58

Necrosis (absence vs presence)

0.08

3.75 (0.69-20.15)

0.12

Intraductal carcinoma (absence vs presence)

0.9

1.87 (0.43-8.10)

0.40

NLR (≤3 vs >3)

0.002

5.15 (1.11 – 23.88)

0.03

  1. Table 2 shows a significant correlation between DFS and higher pre-treatment NLR.
  2. Legend: NLR = Neutrophil to Lymphocyte Ratio; HR = hazard ratio; CI = confidence interval; TNBC = Triple Negative Breast Cancer.