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Table 2 Cox regression analysis for disease-free survival in TNBC

From: Pre-treatment neutrophil to lymphocyte ratio may be a useful tool in predicting survival in early triple negative breast cancer patients

Parameters Univariate Multivariate
p-value HR, 95% CI p-value
Age (≤50 years vs >50 years) 0.12 2.18 (0.02-143.2) 0.74
Menopausal Status (Pre- vs Post-) 0.15 0.80 (0.01-51.3) 0.91
Tumour size (pT1 vs pT2-T3) 0.08 1.81 (0.45-7.14) 0.39
Lymph node status (pN0 vs pN+) 0.2 1.25 (0.31-4.96) 0.74
Nuclear Grade (G1-G2 vs G3) 0.08 0.66 (0.27-1.62) 0.37
Ki-67 (≤20% vs >20%) 0.38 0.78 (0.27-2.26) 0.66
Lympho-vascular invasion (absence vs presence) 0.17 1.68 (0.26-10.70) 0.58
Necrosis (absence vs presence) 0.08 3.75 (0.69-20.15) 0.12
Intraductal carcinoma (absence vs presence) 0.9 1.87 (0.43-8.10) 0.40
NLR (≤3 vs >3) 0.002 5.15 (1.11 – 23.88) 0.03
  1. Table 2 shows a significant correlation between DFS and higher pre-treatment NLR.
  2. Legend: NLR = Neutrophil to Lymphocyte Ratio; HR = hazard ratio; CI = confidence interval; TNBC = Triple Negative Breast Cancer.