Variable | Pathological complete response (pCR) | P-value | |
---|---|---|---|
 |  | OR (95% CI) |  |
CHEK2 H371Y | (MT v WT) | 3.01 (1.34-6.78) | 0.008 |
Age | (≤50 v >50 years) | 1.26 (0.99-1.61) | 0.06 |
Tumor grade | (III v I + II) | 2.28 (1.71-3.03) | <0.001 |
Tumor size | (<2 v ≥2 cm) | 1.76 (1.38-2.24) | <0.001 |
Lymph nodes | (Negative v Positive) | 2.10 (1.63-2.71) | <0.001 |
ER | (Negative v Positive) | 1.99 (1.48-2.67) | <0.001 |
PgR | (Negative v Positive) | 1.65 (1.21-2.26) | 0.002 |
HER2 | (Positive v Negative) | 1.36 (1.05-1.75) | 0.021 |
Trastuzumab use | (Yes v No) | 2.42 (1.47-3.99) | 0.001 |