Skip to main content

Table 2 Age-adjusted incidence rates and incidence rate ratios of small cell lung carcinoma and extrapulmonary small cell carcinoma according to primary site and stage, SEER-13, 1992-2010*

From: A population-based study of incidence and patient survival of small cell carcinoma in the United States, 1992–2010

  Limited Distant Not specified Distant-to-limited
Site No. IR No. IR No. IR IRR (95%CI)
Total 16,142 23.69 35,813 52.51 3,767 5.57 2.22 (2.18, 2.26)
SCLC 14,963 21.98 34,770 50.99 2,226 3.30 2.32 (2.28, 2.37)
EPSCC 1,179 1.71 1,043 1.52 216 0.31 0.89 (0.82, 0.97)
Salivary glands 37 0.06 16 0.02 <16 ~ 0.44 (0.23, 0.81)
Esophagus 73 0.11 93 0.14 21 0.03 1.27 (0.92, 1.75)
Stomach 22 0.03 53 0.08 <16 ~ 2.42 (1.45, 4.17)
Colon/rectum 76 0.11 152 0.22 <16 ~ 1.95 (1.47, 2.61)
Gallbladder 16 0.02 24 0.04 <16 ~ 1.48 (0.75, 2.97)
Pancreas 20 0.03 140 0.21 <16 ~ 6.87 (4.30, 11.61)
Breast (female) 47 0.12 21 0.05 <16 ~ 0.44 (0.25, 0.75)
Cervix 174 0.46 80 0.21 <16 ~ 0.46 (0.35, 0.60)
Uterus 28 0.07 25 0.07 <16 ~ 0.91 (0.51, 1.62)
Ovary 35 0.09 72 0.19 <16 ~ 2.11 (1.38, 3.25)
Prostate 66 0.23 108 0.38 32 0.11 1.62 (1.18, 2.25)
Urinary bladder 390 0.58 123 0.18 16 0.02 0.32 (0.26, 0.39)
  1. Abbreviations: CI confidence interval, EPSCC extrapulmonary small cell carcinoma, No. number of cases, SCLC small cell lung carcinoma, SEER-13 13 cancer registry areas of the Surveillance, Epidemiology and End Results (SEER) Program, ~ IRs are not calculated for <16 cases.
  2. *Incidence rates are age-adjusted to the 2000 U.S. standard population and expressed per 1,000,000 person-years. IRRs are based on unrounded rates. To allow a general overview of stage across primary sites, we used the SEER historic stage variable that includes localized (confined to the organ of origin), regional (direct extension to adjacent organ/tissue or regional lymph nodes), distant (discontinuous metastases), and unspecified stages. We combined localized and regional stages into the category of “limited” stage and maintained the distant stage variable as defined in the SEER Program.
  3. 95 % CI excludes 1.00 (based on unrounded upper and lower CI), and IRR is significant (P < 0.05).