|
Limited
|
Distant
|
Not specified
|
Distant-to-limited
|
---|
Site
|
No.
|
IR
|
No.
|
IR
|
No.
|
IR
|
IRR
|
(95%CI)
|
---|
Total
|
16,142
|
23.69
|
35,813
|
52.51
|
3,767
|
5.57
|
2.22
|
(2.18, 2.26)†
|
SCLC
|
14,963
|
21.98
|
34,770
|
50.99
|
2,226
|
3.30
|
2.32
|
(2.28, 2.37)†
|
EPSCC
|
1,179
|
1.71
|
1,043
|
1.52
|
216
|
0.31
|
0.89
|
(0.82, 0.97)†
|
Salivary glands
|
37
|
0.06
|
16
|
0.02
|
<16
|
~
|
0.44
|
(0.23, 0.81)†
|
Esophagus
|
73
|
0.11
|
93
|
0.14
|
21
|
0.03
|
1.27
|
(0.92, 1.75)
|
Stomach
|
22
|
0.03
|
53
|
0.08
|
<16
|
~
|
2.42
|
(1.45, 4.17)†
|
Colon/rectum
|
76
|
0.11
|
152
|
0.22
|
<16
|
~
|
1.95
|
(1.47, 2.61)†
|
Gallbladder
|
16
|
0.02
|
24
|
0.04
|
<16
|
~
|
1.48
|
(0.75, 2.97)
|
Pancreas
|
20
|
0.03
|
140
|
0.21
|
<16
|
~
|
6.87
|
(4.30, 11.61)†
|
Breast (female)
|
47
|
0.12
|
21
|
0.05
|
<16
|
~
|
0.44
|
(0.25, 0.75)†
|
Cervix
|
174
|
0.46
|
80
|
0.21
|
<16
|
~
|
0.46
|
(0.35, 0.60)†
|
Uterus
|
28
|
0.07
|
25
|
0.07
|
<16
|
~
|
0.91
|
(0.51, 1.62)
|
Ovary
|
35
|
0.09
|
72
|
0.19
|
<16
|
~
|
2.11
|
(1.38, 3.25)†
|
Prostate
|
66
|
0.23
|
108
|
0.38
|
32
|
0.11
|
1.62
|
(1.18, 2.25)†
|
Urinary bladder
|
390
|
0.58
|
123
|
0.18
|
16
|
0.02
|
0.32
|
(0.26, 0.39)†
|
- Abbreviations: CI confidence interval, EPSCC extrapulmonary small cell carcinoma, No. number of cases, SCLC small cell lung carcinoma, SEER-13 13 cancer registry areas of the Surveillance, Epidemiology and End Results (SEER) Program, ~ IRs are not calculated for <16 cases.
- *Incidence rates are age-adjusted to the 2000 U.S. standard population and expressed per 1,000,000 person-years. IRRs are based on unrounded rates. To allow a general overview of stage across primary sites, we used the SEER historic stage variable that includes localized (confined to the organ of origin), regional (direct extension to adjacent organ/tissue or regional lymph nodes), distant (discontinuous metastases), and unspecified stages. We combined localized and regional stages into the category of “limited” stage and maintained the distant stage variable as defined in the SEER Program.
- †95 % CI excludes 1.00 (based on unrounded upper and lower CI), and IRR is significant (P < 0.05).