Table 3 Treatment outcomes according to line of therapy
Line of systemic therapy | Patients receiving therapy, n | Clinician-documented response, n (%) | Treatment duration, months, mean (SD) | Time from initiation of previous therapy to current therapy, months, mean (SD) |
|---|---|---|---|---|
First-line | 99 | 19 (18.8) | 6.0 (7.4) | N/A |
Second-line | 99 | 15 (15.2) | 5.4 (5.3) | 12.3 (13.4) |
Third-line | 78 | 8 (11.1) | 4.1 (4.2) | 9.9 (12.1) |
Fourth-line | 49 | 5 (11.4) | 5.3 (9.1) | 6.2 (5.6) |
Fifth-line | 35 | 4 (12.5) | 4.2 (5.2) | 5.0 (3.6) |
Sixth-line | 20 | 2 (11.1) | 3.2 (3.7) | 7.3 (7.4) |
Seventh-line | 15 | 1 (7.7) | 1.7 (1.1) | 5.7 (6.0) |
Eighth-line | 7 | 1 (16.7) | 4.1 (3.3) | 5.7 (6.5) |
Ninth-line | 6 | 0 (0.0) | 2.2 (2.2) | 7.9 (9.6) |
Tenth-line | 2 | 0 (0.0) | 3.9 (5.0) | 4.4 (1.6) |
Most recent therapy | 99 | 13 (12.9) | 3.6 (6.3) | 8.7 (9.6) |