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Table 3 Treatment outcomes according to line of therapy

From: A retrospective chart review of drug treatment patterns and clinical outcomes among patients with metastatic or recurrent soft tissue sarcoma refractory to one or more prior chemotherapy treatments

Line of systemic therapy Patients receiving therapy, n Clinician-documented response, n (%) Treatment duration, months, mean (SD) Time from initiation of previous therapy to current therapy, months, mean (SD)
First-line 99 19 (18.8) 6.0 (7.4) N/A
Second-line 99 15 (15.2) 5.4 (5.3) 12.3 (13.4)
Third-line 78 8 (11.1) 4.1 (4.2) 9.9 (12.1)
Fourth-line 49 5 (11.4) 5.3 (9.1) 6.2 (5.6)
Fifth-line 35 4 (12.5) 4.2 (5.2) 5.0 (3.6)
Sixth-line 20 2 (11.1) 3.2 (3.7) 7.3 (7.4)
Seventh-line 15 1 (7.7) 1.7 (1.1) 5.7 (6.0)
Eighth-line 7 1 (16.7) 4.1 (3.3) 5.7 (6.5)
Ninth-line 6 0 (0.0) 2.2 (2.2) 7.9 (9.6)
Tenth-line 2 0 (0.0) 3.9 (5.0) 4.4 (1.6)
Most recent therapy 99 13 (12.9) 3.6 (6.3) 8.7 (9.6)
  1. Abbreviations: N/A not available; SD standard deviation.