Table 2 Univariate and multivariate Cox proportional hazard regression analyses of recurrence-free survival
Univariate | Multivariate | |||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Tumor location | ||||
Upper urinary tract vs. Bladder | 0.906 (0.658-1.248) | 0.546 | ||
Age, years | 1.016 (0.999-1.033) | 0.057 | ||
Sex | ||||
Female vs. Male | 1.098 (0.719-1.676) | 0.665 | ||
Body mass index, kg/m2 | 0.947 (0.898-0.999) | 0.049 | 0.980 (0.929-1.033) | 0.453 |
ASA score | ||||
≥2 vs.1 | 0.927 (0.670-1.282) | 0.645 | ||
Hydronephrosis | ||||
Present vs. Absent | 1.609 (1.165-2.221) | 0.004 | 1.378 (0.984-1.928) | 0.062 |
Pathological T category | ||||
pT2 vs. ≤pT1 | 3.588 (1.992-6.461) | <0.001 | 2.875 (1.573-5.256) | 0.001 |
≥pT3 vs. ≤pT1 | 6.748 (4.087-11.141) | <0.001 | 4.675 (2.736-7.990) | <0.001 |
Pathological N category | ||||
pNx vs. pN- | 1.174 (0.810-1.700) | 0.397 | 1.202 (0.805-1.794) | 0.369 |
pN+ vs. pN- | 3.232 (2.113-4.942) | <0.001 | 1.847 (1.180-2.889) | 0.007 |
Tumor grade | ||||
III vs. ≤II | 1.955 (1.416-2.699) | <0.001 | 1.151 (0.802-1.652) | 0.447 |
LVI | ||||
Present vs. Absent | 2.639 (1.911-3.645) | <0.001 | 1.496 (1.042-2.149) | 0.029 |
Associated CIS | ||||
Present vs. Absent | 1.054 (0.681-1.631) | 0.815 | ||
Surgical margin | ||||
Positive vs. Negative | 2.777 (1.675-4.605) | <0.001 | 1.349 (0.797-2.282) | 0.265 |