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Table 2 Univariate and multivariate Cox proportional hazard regression analyses of recurrence-free survival

From: Are urothelial carcinomas of the upper urinary tract a distinct entity from urothelial carcinomas of the urinary bladder? Behavior of urothelial carcinoma after radical surgery with respect to anatomical location: a case control study

  Univariate Multivariate
  HR (95% CI) P value HR (95% CI) P value
Tumor location     
Upper urinary tract vs. Bladder 0.906 (0.658-1.248) 0.546   
Age, years 1.016 (0.999-1.033) 0.057   
Sex     
Female vs. Male 1.098 (0.719-1.676) 0.665   
Body mass index, kg/m2 0.947 (0.898-0.999) 0.049 0.980 (0.929-1.033) 0.453
ASA score     
≥2 vs.1 0.927 (0.670-1.282) 0.645   
Hydronephrosis     
Present vs. Absent 1.609 (1.165-2.221) 0.004 1.378 (0.984-1.928) 0.062
Pathological T category     
pT2 vs. ≤pT1 3.588 (1.992-6.461) <0.001 2.875 (1.573-5.256) 0.001
≥pT3 vs. ≤pT1 6.748 (4.087-11.141) <0.001 4.675 (2.736-7.990) <0.001
Pathological N category     
pNx vs. pN- 1.174 (0.810-1.700) 0.397 1.202 (0.805-1.794) 0.369
pN+ vs. pN- 3.232 (2.113-4.942) <0.001 1.847 (1.180-2.889) 0.007
Tumor grade     
III vs. ≤II 1.955 (1.416-2.699) <0.001 1.151 (0.802-1.652) 0.447
LVI     
Present vs. Absent 2.639 (1.911-3.645) <0.001 1.496 (1.042-2.149) 0.029
Associated CIS     
Present vs. Absent 1.054 (0.681-1.631) 0.815   
Surgical margin     
Positive vs. Negative 2.777 (1.675-4.605) <0.001 1.349 (0.797-2.282) 0.265
  1. Abbreviations: HR = hazard ratio, CI = confidence interval, ASA = American Society of Anesthesiologists, LVI = Lymphovascular invasion, CIS = carcinoma in situ.