Dietary cadmium intake and risk of prostate cancer: a Danish prospective cohort study

BMC Cancer

Table 2 Incidence rate ratios of prostate cancer according to daily dietary cadmium intake

Study population	Dietary cadmium exposure	N cases	Crude model	Adjusted model^a
Study population	Dietary cadmium exposure	N cases	IRR (95% CI)	IRR (95% CI)
Total study group	10 μg increment day⁻¹	1567	1.01 (0.90-1.12)	0.98 (0.88-1.10)
	Tertiles:
	<14 μg day⁻¹	516	1.00	1.00
	14-18 μg day⁻¹	516	0.97 (0.85-1.10)	0.96 (0.85-1.08)
	>18 μg day⁻¹	535	0.99 (0.88-1.12)	0.97 (0.86-1.10)
Subgroups ^b
Aggressive prostate cancer	10 μg increment day⁻¹	840	1.02 (0.88-1.17)	1.00 (0.86-1.16)
Non-aggressive prostate cancer	10 μg increment day⁻¹	327	1.02 (0.81-1.29)	0.99 (0.77-1.25)

Abbreviations:IRR incidence rate ratios, CI confidence interval.
Age is underlying time-scale.
^aAdjusted for educational level (<8 y; 8-10y; >10y), smoking status (never; former; current), BMI (continuous), waist-to-hip ratio (continuous), and physical activity (MET score, continuous).
^bClassification is based on Gleason score, PSA test results at diagnosis, and TNM. Of the 1,567 cases, 400 were excluded in the analyses due to missing information on prostate cancer aggressiveness.

ISSN: 1471-2407