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Table 5 Logistic regression models for predicting TLS formation in breast carcinomas

From: Tertiary lymphoid structures are associated with higher tumor grade in primary operable breast cancer patients

 

Univariate analysis

 

Multivariate analysis

 
 

OR

95% CI

pvalue

OR

95% CI

pvalue

Tumor size (≤20 / 21–50 / >50 mm)

      

≤20 mm

1.00

(Reference)

 

1.00

(Reference)

 

21 - 50 mm

1.40

0.82 - 2.40

0.22

0.84

0.42 - 1.70

0.63

>50 mm

0.20

0.02 - 1.59

0.13

0.14

0.01 - 1.42

0.09

Tumor grade (I / II / III)

      

Grade 1

1.00

(Reference)

 

1.00

(Reference)

 

Grade 2

2.02

1.08 - 3.80

<0.05

1.53

0.72 - 3.26)

0.27

Grade 3

6.53

2.96 - 14.40

<0.01

2.78

1.06 - 7.27

<0.05

Immune cell infiltration (low / high)

13.97

7.78 - 25.09

<0.01

10.80

5.54 - 21.05

<0.01

Lymph node (− / +)

1.65

0.99 - 2.76

0.057

0.98

0.47 - 2.02

0.95

  1. Abbreviations: OR odds ratio, CI confidence interval.