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Table 2 Univariate and multivariate analysis of predictors for overall survival

From: Retrospective analysis of the impact of platinum dose reduction and chemotherapy delays on the outcomes of stage III ovarian cancer patients

 

Univariate model

Multivariate model

Variables

Exp (B)

95.0% CI for Exp (B)

p

Exp (B)

95.0% CI for Exp (B)

p

Lower

Upper

Lower

Upper

Platinum response status (resistant versus sensitive)

3.412

2.002

5.817

<0.001

3.169

1.787

5.620

<0.001

Chemoterapy scheme modification

   

0.035

   

0.050

No Platinum reduction or delay

1

   

1

   

Both Platinum reduction and delay

1.380

0.658

2.896

0.394

1,404

0.615

3.205

0.420

Platinum reduction only

1.388

0.550

3.500

0.487

2,054

0.755

5.586

0.159

Delay only

3.359

1.375

8.204

0.008

3.262

1.248

8,527

0.016

Tumor grade

1.386

0.908

2.115

0.130

1.547

0.936

2.556

0.089

Patients’ age

   

0.225

   

0.260

<=50

1

   

1

   

51–65

0.979

0.531

1.805

0.945

0.723

0.362

1.445

0.359

>65

1.591

0.865

2.926

0.135

1.327

0.653

2.695

0.434

histology (serous versus other)

1.393

0.706

2.750

0.339

1.076

0.518

2.234

0.844

BMI

1.012

0.973

1.053

0.539

    
     

HR

  

p

Delay only versus both reduction and delay

2.323

1.135

4.753

0.021