Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value

Table 1 Top 3 signatures for prognosis prediction

Signature	Significant P value %	Adjusted median P value	Signature description
BRmet50	82%	0.013	Meta-signature for cancer metastasis
PMID18271932Sig33	64%	0.014	Predictor gene set for TP53 status
PMID16505416Sig822	68%	0.015	Poor prognosis signatures for ER+ and PR+ breast cancer

ISSN: 1471-2407