HNRNP G and HTRA2-BETA1 regulate estrogen receptor alpha expression with potential impact on endometrial cancer

BMC Cancer

Table 2 Correlation of ERa standard and ERaD7 expression with clinico-pathological features and HTRA2-BETA1 (Spearman’s correlation test)

Spearman’s		FIGO	Grade	T	LN	M	L	hTra2β1
Spearman’s		(I/II vs III/IV)	(1/2 vs 3)		(P vs N)	(P vs N)	(P vs N)	mRNA
ERα standard	correlation	−0222*	−0.317**	N.S	N.S	N.S	N.S	−0.214*
	coefficient	−0222*	−0.317**	N.S	N.S	N.S	N.S	−0.214*
	p (2-tailed)	0.033	0.001	N.S	N.S	N.S	N.S	0.022
	N	92	116	116	109	86	50	115
ERα∆7	correlation	−0.223*	−0.203*	N.S	−0.206*	N.S	−0.332*	−0.168
	coefficient	−0.223*	−0.203*	N.S	−0.206*	N.S	−0.332*	−0.168
	p (2-tailed)	0.033	0.029	N.S	0.032	N.S	0.019	0.073
	N	92	116	116	109	86	50	116
ERα∆7/standard	correlation	−0.251*	−0.227*	N.S	−0.232*	N.S	−0.407**	−0.198**
	coefficient	−0.251*	−0.227*	N.S	−0.232*	N.S	−0.407**	−0.198**
	p (2-tailed)	0.016	0.014	N.S	0.015	N.S	0.003	0.0034
	N	92	116	116	109	86	50	116

T = Primary tumor; LN = lymph node metastasis; M = distant organ metastasis; L = lymphangiosis; P = positive; N = negative; p = p value; N.S = Not significant; * = significant at the 0.05 level (2-tailed); ** = significant at the 0.001 level.

ISSN: 1471-2407