Table 5 Multivariate Cox model analyses of prognostic factors of CRC in operated group

Years of diagnosis

<0.001

1996-2000

1.000

Reference

2001-2005

0.944

0.930-0.959

Site

<0.001

Colon

1.000

Reference

Rectum

1.044

1.023-1.066

Age

<0.001

15-30

1.055

0.955-1.165

0.294

31-40

0.954

0.906-1.005

0.077

41-50

0.979

0.948-1.011

0.203

51-60

1.000

Reference

61-70

1.082

1.056-1.109

<0.001

71-80

1.325

1.294-1.356

<0.001

>80

1.951

1.902-2.002

<0.001

Pathological grading

<0.001

I- II

1.000

Reference

III-IV

1.443

1.418-1.468

<0.001

Unknown

0.913

0.880-0.948

<0.001

Histological Type

<0.001

Adenocarcinoma

1.000

Reference

Mucinous/Signet ring cancer

1.200

1.175-1.226

AJCC stage

<0.001

I- II

1.000

Reference

III- IV

4.880

4.791-4.971

<0.001

Unknown

1.170

1.130-1.210

<0.001

No. of LNs dissected

<0.001

<12

1.000

Reference

≥12

0.793

0.780-0.806

<0.001

Unknown

2.269

2.183-2.358

<0.001