Table 2 Univariate and multivariate analysis of overall survival in breast cancer patients

S100A14 (positive vs negative)

3.315

1.777 to 6.813

S100A16 (positive vs negative)

2.947

1.640 to 5.927

Co-expression of S100A14 and S100A16 (yes vs no)

3.678

2.029 to 6.666

Age (<60 vs ≥ 60 years)

0.475

0.788

0.660 to 2.439

Tumor size (≥2 cm vs < 2 cm)

0.852

1.060

0.576 to 1.951

Lymph node metastasis (yes vs no)

2.746

1.770 to 4.261

ER (negative vs positive)

0.003

2.351

1.333 to 4.143

PgR (negative vs positive)

0.040

1.948

1.030 to 3.685

HER2 score (2,3 vs 0,1)

2.680

1.492 to 4.815

Histological grade (3 vs 1,2)

4.782

2.653 to 8.618

NS: not significant

Parameter

95% CI

S100A14 (positive vs negative)

3.397

1.807

S100A16 (positive vs negative)

Age (<60 vs ≥ 60 years)

Tumor size (≥2 cm vs < 2 cm)

Lymph node metastasis (yes vs no)

ER (negative vs positive)

PgR (negative vs positive)

0.024

2.107

1.104 to 4.021

HER2 score (2,3 vs 0,1)

Histological grade (3 vs 1,2)

4.316

2.383 to 7.817

NS: not significant

Parameter

95% CI

Co-expression of S100A14 and S100A16 (yes vs no)

0.001

2.811

1.529 to 5.170

Age (<60 vs ≥ 60 years)

Tumor size (≥2 cm vs < 2 cm)

Lymph node metastasis (yes vs no)

ER (negative vs positive)

PgR (negative vs positive)

0.049

1.907

1.004 to 3.623

HER2 score (2,3 vs 0,1)

Histological grade (3 vs 1,2)

3.970

2.175 to 7.247

NS: not significant