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Table 1 Association between clinicopathological variables and S100A14 and S100A16

From: Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion

Clinical data S100A14   S100A16   S100A14 and S100A16  
Low expression High expression   Low expression High expression   Low expression High expression  
P P P
n = 84 (%) n = 83 (%)   n = 132 (%) n = 35 (%)   n = 137 (%) n = 30 (%)  
Patient age (y)          
<60 53(31.7) 65(38.9) 0.047* 88(52.7) 30(18.0) 0.046* 93(55.7) 25(15.0) 0.025*
≥60 31(18.6) 18(10.8)   44(26.3) 5(3.0)   44(26.3) 5(3.0)  
pT          
1 29(17.4) 20(12.0) 0.183 46(27.5) 3(1.8) 0.007§ 47(28.1) 2(1.2) 0.07
2 49(29.3) 52(31.1)   73(43.7) 28(16.8)   77(46.1) 24(14.4)  
3 6(3.6) 8(4.8)   11(6.6) 3(1.8)   11(6.6) 3(1.8)  
4 0(0) 3(1.8)   2(1.2) 1(0.6)   2(1.2) 1(0.6)  
pN          
0 30(18.0) 22(13.2) 0.153 51(30.5) 1(0.6) <0.001§ 51(30.5) 1(0.6) 0.005§
1 50(29.9) 50(29.9)   71(42.5) 29(17.4)   76(45.5) 24(14.4)  
2 4(2.4) 10(6.0)   10(6.0) 4(2.4)   10(6.0) 4(2.4)  
3 0(0) 1(0.6)   0(0) 1(0.6)   0(0) 1(0.6)  
TNM staging          
I 25(15.0) 15(9.0) 0.126 37(22.2) 3(1.8) 0.067 37(22.2) 3(1.8) 0.214
II 50(29.9) 50(29.9)   75(44.9) 25(15.0)   80(47.9) 20(12.0)  
III 8(4.8) 14(8.4)   16(9.6) 6(3.6)   16(9.6) 6(3.6)  
IV 1(0.6) 4(2.4)   4(2.4) 1(0.6)   4(2.4) 1(0.6)  
Histological grade          
1 26(15.6) 13(7.8) 0.069 33(19.8) 6(3.6) 0.433 36(21.6) 3(1.8) 0.147
2 36(21.6) 43(25.7)   63(37.7) 16(9.6)   65(38.9) 14(8.4)  
3 22(13.2) 27(16.2)   36(21.6) 13(7.8)   36(21.6) 13(7.8)  
ER          
Negative 23(13.8) 39(23.4) 0.014* 43(25.7) 19(11.4) 0.030* 44(26.3) 18(10.8) 0.008*
Positive 61(36.5) 44(26.3)   89(53.3) 16(9.6)   93(55.7) 12(7.2)  
PgR          
Negative 53(31.9) 50(29.9) 0.826 80(47.9) 23(13.8) 0.721 83(49.7) 20(12.0) 0.618
Positive 31(18.7) 33(19.9)   52(31.1) 12(7.2)   54(32.3) 10(6.0)  
HER2          
score 0 & 1 76(45.4) 56(33.1) 0.001* 114(68.3) 18(10.8) <0.001* 118(70.7) 14(8.4) <0.001*
score 2 & 3 8(4.9) 27(16.6)   18(10.8) 17(10.2)   19(11.4) 16(.96)  
S100A16          
low 79(47.3) 53(31.7) <0.001*       
high 5(3.0) 30(18.0)        
  1. *p <0.05 for χ2 test with Yates correction.
  2. §p <0.05 for Fisher’s exact test.