BMC Cancer

Table 1 Demographic characteristics of the study subjects (CRC cases and controls) by phase

From: Plasma clusterin as a candidate pre-diagnosis marker of colorectal cancer risk in the Florence cohort of the European Prospective Investigation into Cancer and Nutrition: a pilot study

Phase 1
Characteristic	Cases N	Controls N	Total N	P-value^a
Sex
M	7	9	16	0.58
F	3	1	4
Smoker				0.20
Current	2	1	3
Former	5	2	7
Never	3	7	10
Total	10	10	20
Age (yrs.) mean (SD)	61.6 (11.1)	60.2 (10.9)	60.9 (10.8)	0.89
*Phase 2*
Characteristic	Cases N	Controls N	Total N	P-value ^a
Sex				1.0
M	4	4	8
F	6	6	12
Smoker				0.08
Current	4	0	4
Former	1	2	3
Never	5	8	13
Total	10	10	20
Age (yrs.) mean (SD)	53.3 (7.8)	53.3 (7.6)	53.3 (7.5)	0.91
*Phase 3*
Characteristic	Cases N ^c	Controls N	Total N	P-value ^a
Sex				1.00
M	20	20	40
F	28	28	56
Smoker				0.22
Current	16	10	26
Former	15	13	28
Never	17	25	42
Waistline ^b				0.67
≤ OMS cut-off	35	39	74
> OMS cut-off	8	7	15
BMI ^b				0.13
Normal	17	24	41
Overweight	26	17	43
Obesity	3	6	9
School				0.12
Primary	16	7	23
Secondary	23	32	55
High	9	9	18
Total	48	48	96
Age (yrs.) mean (SD)	55.1 (6.2)	55.2 (6.2)	55.1 (6.1)	0.98
Daily Consumption (g)
Characteristic	Cases	Controls	Total	P-value ^a
Fruit intake	258.3 (114.8)	380.4 (192.6)	319.4 (153.7)	0.0003
Vegetables	160.9 (75.3)	232.4 (117.6)	196.7 (96.5)	0.0006
Red meat	74.3 (49.4)	67.1 (45.0)	70.7 (47.2)	0.46
Alcohol	22.8 (22.3)	15.2 (16.5)	19.0 (19.4)	0.06

^aP-values from chi-square or Mann–Whitney test, as appropriate.
^bSome data are missing.
^cCRC location according to ICD-O classification: Cecum, n = 4; Ascending colon, n = 6; Hepatic flexure colon, n = 1; Transverse colon, n = 0; Splenic flexure colon, n = 1; Descending colon, n = 4; Sigmoid colon, n = 15; Colon NOS, n = 5; Rectosigmoid junction, n = 5; Rectum, n = 7.

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ISSN: 1471-2407

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