Table 2 Pooled estimates of SNC relative risk and 95% confidence intervals by histologic subgroup (AC, SCC) for each exposure
From: Occupational exposure and sinonasal cancer: a systematic review and meta-analysis
| Â | All | Adenocarcinoma (AC) | Squamous cell CA (SCC) | Exposure |
|---|---|---|---|---|
RR pooled (95% CI) | 5.91 (4.31-8.11) | 29.43 (16.46-52.61) | 1.46 (1.01-2.1) | Wood dust |
Between studies variance (Ï„2) | 1.93 | 1.10 | 0 | |
Q statistic (df, p-value) | 909.1 (87, <0.01) | 81.1 (16, <0.01) | 4.72 (10, 0.909) | |
I 2 | 90.4 | 80.3 | 0 | |
RR pooled (95% CI) | 11.89 (7.69-18.36) | 35.26 (20.62-60.28) | 2.09 (1.12-3.9) | Leather dust |
Between studies variance (Ï„2) | 0.75 | 0 | 0 | |
Q statistic (df, p-value) | 61.3 (30, <0.01) | 5.18 (9, 0.818) | 0.82 (6, 1) | |
I 2 | 51.0 | 0 | 0 | |
RR pooled (95% CI) | 1.68 (1.37-2.06) | 3.81 (1.39-10.41) | 2.37 (1.69-3.33) | Formaldehyde |
Between studies variance (Ï„2) | 0.15 | 0.39 | 0 | |
Q statistic (df, p-value) | 59.0 (31, <0.01) | 4.0 (2, 0.14) | 0.9 (4, 0.92) | |
I 2 | 47.5 | 49.9 | 0 | |
RR pooled (95% CI) | 2.03 (1.47-2.8) | 3.50 (1.88-6.54) | 0.85 (0.40-1.8) | Textile industry |
Between studies variance (Ï„2) | 0.47 | 0.47 | 0 | |
Q Statistic (df, p-value) | 92.8 (28, <0.01) | 24.08 (6, <0.01) | 0.78 (2, 0.676) | |
I 2 | 69.8 | 75.1 | 0 | |
RR pooled (95% CI) | 1.01 (0.75-1.36) | 0.38 (0.21-0.69) | 1.30 (0.90-1.88) | Farming |
Between studies variance (Ï„2) | 0.28 | 0 | 0.07 | |
Q statistic (df, p-value) | 50.8 (23, <0.01) | 2.38 (3, 0.497) | 8.6 (6, 0.2) | |
I 2 | 54.8 | 0 | 30.2 | |
RR pooled (95% CI) | 1.62 (1.11-2.36) | 0.90 (0.39-2.08) | 2.15 (1.01-4.58) | Construction |
Between studies variance (Ï„2) | 0.48 | 0 | 0.45 | |
Q statistic (df, p-value) | 57.6 (22, <0.01) | 0.16 (1, 0.691) | 11.88 (4, 0.02) | |
I 2 | 61.8 | 0 | 66.3 | |
RR pooled (95% CI) | 18.0 (14.55-22.27) | Â | Â | Nickel/Chromium compounds |
Between studies variance (Ï„2) | 0.19 | - | - | |
Q statistic (df, p-value) | 3268.0 (24, <0.01) | Â | Â | |
I 2 | 99.3 | Â | Â |