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Table 2 Pooled estimates of SNC relative risk and 95% confidence intervals by histologic subgroup (AC, SCC) for each exposure

From: Occupational exposure and sinonasal cancer: a systematic review and meta-analysis

  All Adenocarcinoma (AC) Squamous cell CA (SCC) Exposure
RR pooled (95% CI) 5.91 (4.31-8.11) 29.43 (16.46-52.61) 1.46 (1.01-2.1) Wood dust
Between studies variance2) 1.93 1.10 0
Q statistic (df, p-value) 909.1 (87, <0.01) 81.1 (16, <0.01) 4.72 (10, 0.909)
I 2 90.4 80.3 0
RR pooled (95% CI) 11.89 (7.69-18.36) 35.26 (20.62-60.28) 2.09 (1.12-3.9) Leather dust
Between studies variance2) 0.75 0 0
Q statistic (df, p-value) 61.3 (30, <0.01) 5.18 (9, 0.818) 0.82 (6, 1)
I 2 51.0 0 0
RR pooled (95% CI) 1.68 (1.37-2.06) 3.81 (1.39-10.41) 2.37 (1.69-3.33) Formaldehyde
Between studies variance2) 0.15 0.39 0
Q statistic (df, p-value) 59.0 (31, <0.01) 4.0 (2, 0.14) 0.9 (4, 0.92)
I 2 47.5 49.9 0
RR pooled (95% CI) 2.03 (1.47-2.8) 3.50 (1.88-6.54) 0.85 (0.40-1.8) Textile industry
Between studies variance2) 0.47 0.47 0
Q Statistic (df, p-value) 92.8 (28, <0.01) 24.08 (6, <0.01) 0.78 (2, 0.676)
I 2 69.8 75.1 0
RR pooled (95% CI) 1.01 (0.75-1.36) 0.38 (0.21-0.69) 1.30 (0.90-1.88) Farming
Between studies variance2) 0.28 0 0.07
Q statistic (df, p-value) 50.8 (23, <0.01) 2.38 (3, 0.497) 8.6 (6, 0.2)
I 2 54.8 0 30.2
RR pooled (95% CI) 1.62 (1.11-2.36) 0.90 (0.39-2.08) 2.15 (1.01-4.58) Construction
Between studies variance2) 0.48 0 0.45
Q statistic (df, p-value) 57.6 (22, <0.01) 0.16 (1, 0.691) 11.88 (4, 0.02)
I 2 61.8 0 66.3
RR pooled (95% CI) 18.0 (14.55-22.27)    Nickel/Chromium compounds
Between studies variance2) 0.19 - -
Q statistic (df, p-value) 3268.0 (24, <0.01)   
I 2 99.3