From: Serum HE4 detects recurrent endometrial cancer in patients undergoing routine clinical surveillance
No recurrence (n = 73) | Recurrence (n = 26) | P value | |
---|---|---|---|
Age | |||
Median (IQR) | 63 (57–71) | 71 (64–77) | 0.002a |
FIGO Stage | |||
1 | 46 (63) | 12 (46) | 0.064b |
2 | 4 (5) | 3 (12) | |
3 | 20 (27) | 5 (19) | |
4 | 2 (3) | 6 (23) | |
Histology | |||
Endometrioid | 50 (69) | 19 (73) | 0.685b |
Serous Papillary/Clear cell | 16 (23) | 5 (19) | |
Carcinosarcoma | 6 (8) | 2 (8) | |
Lymph nodes | |||
LN negative | 58 (80) | 18 (72) | 0.500c |
LN positive | 13 (20) | 7 (28) | |
Unknown | 1 | 1 | |
Grade | |||
1 | 14 (19) | 3 (12) | 0.841b |
2 | 27 (37) | 12 (46) | |
3 | 30 (43) | 11 (42) | |
Unknown | 1 | ||
Risk status | |||
Low risk | 18 (25) | 11 (42) | 0.089c |
High risk | 54 (75) | 15 (58) | |
Adjuvant treatment | |||
No Adjuvant treatment | 5 (6) | 2 (8) | 0.297b |
Radiotherapy | 44 (60) | 10 (39) | |
Chemotherapy | 10 (14) | 9 (35) | |
Chemotherapy + radiotherapy | 14 (20) | 5 (19) | |
Median follow-up | 5.36 (0.6–12.6) | 2.63 (0.6–8.6) | |
(Years (range)) |