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Table 2 Clinico-pathological characteristics stratified based on recurrence status

From: Serum HE4 detects recurrent endometrial cancer in patients undergoing routine clinical surveillance

 

No recurrence (n = 73)

Recurrence (n = 26)

P value

Age

   

Median (IQR)

63 (57–71)

71 (64–77)

0.002a

FIGO Stage

   

1

46 (63)

12 (46)

0.064b

2

4 (5)

3 (12)

 

3

20 (27)

5 (19)

 

4

2 (3)

6 (23)

 

Histology

   

Endometrioid

50 (69)

19 (73)

0.685b

Serous Papillary/Clear cell

16 (23)

5 (19)

 

Carcinosarcoma

6 (8)

2 (8)

 

Lymph nodes

   

LN negative

58 (80)

18 (72)

0.500c

LN positive

13 (20)

7 (28)

 

Unknown

1

1

 

Grade

   

1

14 (19)

3 (12)

0.841b

2

27 (37)

12 (46)

 

3

30 (43)

11 (42)

 

Unknown

1

  

Risk status

   

Low risk

18 (25)

11 (42)

0.089c

High risk

54 (75)

15 (58)

 

Adjuvant treatment

   

No Adjuvant treatment

5 (6)

2 (8)

0.297b

Radiotherapy

44 (60)

10 (39)

 

Chemotherapy

10 (14)

9 (35)

 

Chemotherapy + radiotherapy

14 (20)

5 (19)

 

Median follow-up

5.36 (0.6–12.6)

2.63 (0.6–8.6)

 

(Years (range))

   
  1. Values in parenthesis are percentages unless otherwise stated. IQR – interquartile range, FIGO - International Federation of Gynecology and Obstetrics, LN – lymph node. aMann–Whitney U test, bSpearman’s Correlation, cPearson Chi Squared test.