Figure 2
From: Serum HE4 detects recurrent endometrial cancer in patients undergoing routine clinical surveillance
HE4 is a superior predictor of recurrent disease than CA125. Receiver operator curves (ROC) comparing HE4 to CA125 for identify patients with recurrent endometrial cancer in all evaluated patients (n = 98) (A) and those with endometrioid histology (n = 69) (B). A regression model combining age, CA125 and HE4 did not improve the sensitivity or specificity of HE4 to identify recurrent disease in the entire cohort (n = 98) (C). AUC = area under the curve. Values in parenthesis are 95% confidence interval.