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Table 2 Correlation of EphA5 methylation and mRNA expression with clinical and histological parameters in PCa patients

From: Downregulation of EphA5 by promoter methylation in human prostate cancer

  Methylation p-value1 mRNA expression p-value1
Present Absent Normal Reduced
Age (years)
≤70 18 7 0.883 8 17 0.371
>70 14 6 9 11
PSA (ng/ml)
≤10 6 3 0.742 2 7 0.537
>10 26 10 15 21
Stage (TNM)
T1-T2 6 7 0.019 7 6 0.156
T3-T4 26 6 10 22
Gleason score
6-7 12 10 0.016 12 10 0.023
8-10 20 3 5 18
Prostate volume (ml)
≤50 24 7 0.165 11 20 0.637
>50 8 6 6 8
  1. Normal: 0.5 ≤ 2-Ct ≤2; Reduced: 2-Ct < 0.5; 1χ2 (2-tailed).