Prognostic survival model for people diagnosed with invasive cutaneous melanoma

BMC Cancer

Table 4 Evaluation of heterogeneity of the measure of separation (Discrimination, D) across geographically defined regions: internal–external cross-validation using the MSI model

Region (k)¹	N_k	Melanoma deaths_k	Other deaths_k	D_(k)Omitting region k	D_kPredicted in region k	d_k(= D_k– D_(k))	SE (d_k)
1	1,294	84	150	1.50	1.57	0.07	0.14
2	1,438	80	151	1.50	1.51	0.01	0.14
3	919	54	101	1.49	2.34	0.85	0.24
4	1,574	91	192	1.49	1.73	0.24	0.14
5	1,461	104	204	1.50	1.52	0.01	0.13
6	2,313	138	287	1.49	1.75	0.26	0.12
7	3.495	216	446	1.53	1.38	−0.15	0.08
8	10,578	601	1,376	1.52	1.46	−0.06	0.06
9	3,982	212	489	1.53	1.40	−0.13	0.09

¹Cases for which the geographical region was undefined (n = 1,600, 120 melanoma deaths, 373 other deaths) were retained in the validation process.

ISSN: 1471-2407