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Table 4 Evaluation of heterogeneity of the measure of separation (Discrimination, D) across geographically defined regions: internal–external cross-validation using the MSI model

From: Prognostic survival model for people diagnosed with invasive cutaneous melanoma

Region (k)1 Nk Melanoma deathsk Other deathsk D(k)Omitting region k DkPredicted in region k dk(= Dk– D(k)) SE (dk)
1 1,294 84 150 1.50 1.57 0.07 0.14
2 1,438 80 151 1.50 1.51 0.01 0.14
3 919 54 101 1.49 2.34 0.85 0.24
4 1,574 91 192 1.49 1.73 0.24 0.14
5 1,461 104 204 1.50 1.52 0.01 0.13
6 2,313 138 287 1.49 1.75 0.26 0.12
7 3.495 216 446 1.53 1.38 −0.15 0.08
8 10,578 601 1,376 1.52 1.46 −0.06 0.06
9 3,982 212 489 1.53 1.40 −0.13 0.09
  1. 1Cases for which the geographical region was undefined (n = 1,600, 120 melanoma deaths, 373 other deaths) were retained in the validation process.