|
Age
|
<65 yr vs. ≥65 yr
|
1.26
|
[0.50-3.17]
|
0.62
|
|
Gender
|
Female vs. Male
|
0.59
|
[0.23-1.49]
|
0.27
|
|
Smoking status
|
Never smoker vs. Ever smoker
|
0.41
|
[0.15-1.13]
|
0.08
|
|
Stage
|
III vs. IV/Relapse
|
1.46
|
[ 0.34-6.37]
|
0.61
|
|
EGFR mutation type
|
Exon19 deletion vs. Exon 21 L858R
|
1.90
|
[0.72-5.00]
|
0.62
|
|
MET FISH
|
Negative vs. Positive
|
2.25
|
[1.07-4.74]
|
0.03
|
|
Hazard ratios for progression in according to prognostic factors
|
|
Characteristics
|
Comparison
|
Hazard ratio [95% CI
a
]
|
P value
b
|
|
Age
|
<65 yr vs. ≥65 yr
|
0.52
|
[0.23-1.15]
|
0.11
|
|
Gender
|
Female vs. Male
|
0.88
|
[0.40-1.93]
|
0.75
|
|
Smoking stutus
|
Never smoker vs. Ever smoker
|
1.11
|
[0.51-2.42]
|
0.79
|
|
Stage
|
III vs. IV/Relapse
|
1.04
|
[0.30-3.64]
|
0.95
|
|
EGFR mutation type
|
Exon19 deletion vs. Exon 21 L858R
|
1.15
|
[0.45-2.91]
|
0.77
|
|
MET FISH
|
Negative vs. Positive
|
3.83
|
[1.75-8.38]
|
0.0008
|
