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Table 3 Univariate Cox proportional hazards models of factors associated with death and progression for all cases

From: MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation

Hazard ratios for death in according to prognostic factors
Characteristics Comparison Hazard ratio [95% CI a ] P value b
Age <65 yr vs. ≥65 yr 1.26 [0.50-3.17] 0.62
Gender Female vs. Male 0.59 [0.23-1.49] 0.27
Smoking status Never smoker vs. Ever smoker 0.41 [0.15-1.13] 0.08
Stage III vs. IV/Relapse 1.46 [ 0.34-6.37] 0.61
EGFR mutation type Exon19 deletion vs. Exon 21 L858R 1.90 [0.72-5.00] 0.62
MET FISH Negative vs. Positive 2.25 [1.07-4.74] 0.03
Hazard ratios for progression in according to prognostic factors
Characteristics Comparison Hazard ratio [95% CI a ] P value b
Age <65 yr vs. ≥65 yr 0.52 [0.23-1.15] 0.11
Gender Female vs. Male 0.88 [0.40-1.93] 0.75
Smoking stutus Never smoker vs. Ever smoker 1.11 [0.51-2.42] 0.79
Stage III vs. IV/Relapse 1.04 [0.30-3.64] 0.95
EGFR mutation type Exon19 deletion vs. Exon 21 L858R 1.15 [0.45-2.91] 0.77
MET FISH Negative vs. Positive 3.83 [1.75-8.38] 0.0008
  1. a Abbreviation: CI Confidence interval.
  2. bCox regression analysis. P values of < .05 are shown in bold.