Analysis of the cell cycle and apoptosis in HeLa cells after treatments. Cell-cycle distribution was expressed as the percentage of surviving cells compared to the number of cells in the untreated control at 24 h (A), 48 h (B) and 72 h (C). Values represent the mean ± SD. *p < 0.05 (comparing MF or ICI combined with cisplatin/radiation treatment to the treatment with only cisplatin/radiation). Apoptosis was measured by surface AnV staining and flow cytometry, and it was considered positive for AnV+/PI- cells (D). Values represent the mean ± SD *p < 0.05 (comparing MF or ICI combined with radiation/cisplatin to the treatment with only radiation/cisplatin).