Table 4 ES - SBA - overall survival BY prognostic factors
Number events/Number subjects | 5 Year survival (95% CI) | Hazard ratio (95% CI) | p-value | ||
|---|---|---|---|---|---|
Gender | Male | 15/28 | 41.0 (19.8 – 62.2) | 1.81 (0.79 – 4.15) | 0.160 |
Female | 9/20 | 55.5 (33.2 – 76.8) | - | ||
Primary tumour | Duodenum | 12/30 | 60.3 (40.9 – 79.7) | - | (0.046) |
Jejunum | 7/10 | 30.0 (1.6 – 58.4) | 1.61 (0.63 – 4.11) | 0.316 | |
Ileum | 4/7 | 33.3 (0 – 70.9) | 1.97 (0.63 – 6.22) | 0.246 | |
Small bowel unknown | 1/1 | 0 | 28.4 (2.48 – 326.5) | 0.007 | |
Grade | Low/(differentiation) | 10/27 | 56.9 (36.7 – 77.1) | - | |
Moderate | Poor | 14/20 | 34.8 (12.7 – 56.9) | 2.58 (1.13 – 5.89) | 0.025 |
Nodes harvested | <12 | 12/21 | 42.9 (21.7 – 64.1) | - | |
≥12 | 6/16 | 69.6 (44.3 – 94.9) | 0.75 (0.28 – 2.01) | 0.572 | |
Nodes involved | Negative (Stage I/II) | 13/30 | 49.7 (30.1 – 69.3) | - | |
Positive (Stage III) | 9/12 | 41.7 (13.9 – 69.5) | 1.64 (0.70 – 3.84) | 0.259 | |
LVI | No | 3/18 | 78.6 (57.0 – 100) | - | |
Yes | 17/22 | 30.0 (10.4 – 49.6) | 6.73 (1.95 – 23.2) | 0.003 | |
PNI | No | 13/29 | 51.4 (31.4 – 71.4) | - | |
Yes | 7/11 | 45.5 (16.1 – 74.9) | 1.42 (0.56 – 3.55) | 0.460 | |
Adjuvant Chemo | No | 10/21 | 42.0 (18.5 – 65.5) | - | |
Yes | 14/27 | 52.1 (32.3 – 71.9) | 0.93 (0.41 – 2.11) | 0.867 | |
Small Bowel Obstruction | None | 13/28 | 46.9 (26.9 – 66.9) | - | |
Present | 5/8 | 29.2 (0 – 63.1) | 1.75 (0.62 – 4.97) | 0.294 | |
Weight loss | None | 14/29 | 45.0 (25.6 – 64.4) | - | |
Present | 4/7 | 33.3 (0 – 70.9) | 1.92 (0.63 – 5.84) | 0.252 | |
CEA at baseline | Normal | 7/21 | 65.0 (44.0 – 86.0) | 2.29 (0.90 – 5.82) | 0.082 |
Abnormal | 12/17 | 37.5 (13.8 – 61.2) | - | ||
Hemoglobin | Normal | 7/14 | 44.5 (16.5 – 72.5) | - | |
Abnormal | 15/24 | 43.5 (23.3 – 63.7) | 1.27 (0.52 – 3.31) | 0.604 | |
Albumin | Normal | 12/22 | 46.7 (24.9 – 68.5) | - | |
Abnormal | 10/16 | 40.0 (15.3 – 64.7) | 1.14 (0.49 – 2.65) | 0.756 | |
LDH | Normal | 7/13 | 48.0 (18.6 – 77.4) | - | |
Abnormal | 7/12 | 50.0 (21.8 – 78.2) | 0.87 (0.30 – 2.52) | 0.874 | |
Alk.Ph | Normal | 14/24 | 43.1 (22.5 – 63.7) | - | |
Abnormal | 8/14 | 46.2 (19.2 – 73.2) | 0.75 (0.31 – 1.79) | 0.512 | |
ALT | Normal | 16/29 | 46.0 (27.4 – 64.6) | - | |
Abnormal | 5/8 | 42.9 (6.2 – 79.6) | 1.05 (0.38 – 2.89) | 0.921 | |
Platelets | Normal | 21/43 | 50.9 (35.0 – 66.8) | - | |
Abnormal | 1/2 | 0 | 6.68 (0.77 – 57.6) | 0.084 |