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Table 1 The IC50 (μM) of curcumin and its analogues, GO-Y030, FLLL-11, and FLLL-12 in human colon cancer cells and WI-38 human lung fibroblasts

From: New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

  HCT116
(IC50 μM)
HT-29
(IC50 μM)
SW480
(IC50 μM)
WI-38
(IC50 μM)
Curcumin 10.91 13.31 10.26 48.82
GO-Y030 0.61 0.96 0.51 13.78
FLLL-11 2.07 4.48 1.64 >1000.00
FLLL-12 2.49 3.35 1.17 >1000.00
  1. *Cancer cells were treated for 72 hours and cell viability was determined by MTT assays and IC50 values were analyzed.