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Figure 2 | BMC Cancer

Figure 2

From: Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma

Figure 2

Intratumoral heterogeneity of HER-2 gene status detected by chromogen in situ hybridization in two different areas (areas 1 and 2) from three breast tumors (A, B, and C). Nonamplified HER-2 gene (2–5 copies per nucleus), low-level amplification (6–10 copies or small clusters) and high-level amplification (>10 copies or large clusters) were observed in different areas from the same tumor. FISH results of the same cases are represented on the right side of the figure.

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BMC Cancer

ISSN: 1471-2407

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