Figure 1From: Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma Breast cancer cells showing immunohistochemistry and chromogen in situ hybridization results of HER-2. (A-D) IHC: HER-2 protein expression scored as 0 (A), 1+ (B), 2+ (C), and 3+ (D); (E-H) CISH: HER-2 gene detected in nuclei with two signals (E), more than two signals (F), and high-level amplification (G-H).Back to article page