Post-operative CK18-Asp396, total CK18 and CK18-Asp396/CK18 ratios levels, and survival. Post-operative (P3) CK18-Asp396 and total CK18 levels of colorectal cancer patients with a Dukes' A/B vs Dukes' C/D stage carcinoma (A and B). Box plots with line indicating median value, box indicating IQR and bars indicating the range. Kaplan Meier disease-free survival curves of all colorectal cancer patients, groups divided upon median post-operative CK18-Asp396 (C, n = 28) and total CK18 levels (D, n = 28). Plasma CK18-Asp396/CK18 ratios were decreased in patients Dukes' C/D vs Dukes' A/B (E). Kaplan Meier disease-free survival curves of colorectal cancer patients, groups divided upon median post-operative plasma CK18-Asp396/CK18 ratios (F, n = 28).