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Table 1 Clinical characteristics and YKL-40 expression in tumor tissue and plasma YKL-40 levels from patients diagnosed with borderline ovarian tumor#

From: YKL-40 tissue expression and plasma levels in patients with ovarian cancer

Characteristic   YKL-40 protein expression (N = 181)   Plasma YKL-40 (μg/l) (N = 19)
  N (%) Median (range) N (%) Median (range)
FIGO stage:     
I 160 (88) 5 (0–90) 19 (100) 42 (20–180)
II 5 (3) 5 (0–30)   
III 16 (9) 7.5 (0–30)   
Histological type of tumor:     
Cystadenoma (NOS), borderline 14 (8) 7.5 (5–20) 2 (10) 39 (38–40)
Serous cystadenoma, borderline 95 (52) 5 (0–80) 6 (32) 42 (31–142)
Mucinous cystadenoma, borderline 69 (38) 5 (0–90) 11 (58) 37 (20–180)
Endometroid cystadenoma, borderline 3 (2) 5 (5–40)   
  1. # Scoring of YKL-40 expression was based on the proportion of cells in a given tumor specimen exhibiting distinct cytoplasmic immunopositivity as well as intensity of staining percentage scale: 0, 5, 10, 20, 30, 40, 50, 60, 70, 80, 90, and 100. The YKL-40 scoring results was transformed into a four-tiered scale: 1 = negative; 2 = 5% positive tumor cells; 3 = 10% positive tumor cells and 4 = 20% or more positive tumor cells.