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Table 3 C2-O-sLex was compared to sLex expression in primary colorectal adenocarcinomas and metastatic liver tumors.

From: The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 β-1,6-N-acetylglusaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas

  Differentiation Status
  Well differentiated Moderately differentiated Poorly differentiated
Antibody staining reactivity in colorectal adenocarcinomas 0+ (NE) 0+ (1+)* NE (NE)
  1+ (2+)* 1+ (1+) 1+ (3+)*
  2+ (2+) 2+ (3+)* 2+ (3+)*
  3+ (3+) 3+ (3+) 3+ (3+)
Antibody staining reactivity in metastatic liver tumors NE (NE) 0+ (0+) NE (NE)
  NE (NE) 1+ (2+)* NE (NE)
  2+ (2+) 2+ (2+) 2+ (3+)*
  3+ (2+) 3+ (3+) 3+ (3+)
  1. Serial sections of individual tissues were stained with CHO-131 mAb that detects C2-O-sLex and CSLEX1 mAb that detects sLex. The numbers in the body of the table indicate the intensity of reactivity of a representative single tissue with CHO-131 mAb. The bracketed numbers indicate the intensity of reactivity of a serial section of the same tissue with CSLEX1 mAb. NE = not examined. * indicates a difference in reactivity between CHO-131 and CSLEX1 mAbs.