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Table 5 Risk assessment among different loci of HLA class II

From: High resolution human leukocyte antigen (HLA) class I and class II allele typing in Mexican mestizo women with sporadic breast cancer: case-control study

 

CASES

N = 174

CONTROLS

N = 186

   

Locus

n

g.f

n

g.f

P

OR

C195%

HLA-DRB1

       

0802

27

0.155

25

0.134

0.682

1.183

0.657–2.130

0407

22

0.126

33

0.177

0.231

0.671

0.374–1.204

1406

14

0.080

15

0.081

0.851

0.998

0.467–2.132

1301

7

0.040

1

0.005

0.06

7.754

0.944–63.689

1602

7

0.040

0

0

0.025

16.701

0.947–294.670*

HLA-DQB1

       

0302

79

0.454

51

0.274

0.0001

2.201

1.419–3.415**

0402

29

0.167

28

0.151

0.784

1.129

0.641–1988

0202

18

0.103

10

0.054

0.118

2.031

0.910–4.531

0301

4

0.022

43

0.231

0.00001

0.078

0.027–0.223***

0201

2

0.011

0

0

0.524

5.406

0.258–113.402

0303

1

0.005

2

0.011

0.954

0.532

0.048–5.918

  1. * Pc = 0.24. **Pc = 0.0007 ***Pc = 00008