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Table 1 Cell viabilities of Compound K in various cancer cell lines in vitro

From: Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells

Cell lines IC50 (μM)a
HL-60 14.1
U937 16.5
HeLa 29.9
A549 37.9
HepG2 59.4
P388 18.4
A431 37.9
  1. aIC50 is defined as the concentration that results in a 50% decrease in the number of cells compared to that of the control cultures in the absence of Compound K. The values represent the means of results from three independent experiments with similar patterns.