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Table 4 Interaction of ERCC1 and XRCC1 polymorphisms on survival of lung adenocarcinoma

From: Association between polymorphisms in DNA repair genes and survival of non-smoking female patients with lung adenocarcinoma

 

ERCC1CC

ERCC1 CT/TT

XRCC1

MST

HR(95%CI)A

MST

HR(95%CI)A

GG

25.10

1.00

13.30

1.79(1.16-2.76)

GA/AA

12.47

1.64(1.11-2.44)

8.60

2.44(1.63-3.65)

  1. Abbreviation: MST, median survival time; HR, hazard ratio; CI, confidence interval.
  2. AHR and 95%CI were calculated by Cox regression, with the ERCC1 wild genotype (CC) and XRCC1 wild genotype (GG) as the reference group;HRs were adjusted for age, stage, surgical operation and chemotherapy or radiotherapy.