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Table 3 Associations according to age stratification

From: Nuclear receptor coregulator SNP discovery and impact on breast cancer risk

SNP Genotypes Cases Controls OR 95% CI P
Cases and Controls ≥50
SRC-1 CC (%) 306 (93.9) 747 (94.9) 1   
rs1804645 CT (%) 20 (6.1) 40 (5.1) 1.22 0.70-2.12 0.479
P1272S TT (%) 0 (0.0) 0 (0.0) - - -
   [CT + TT]<-> [CC] 1.22 0.70-2.12 0.479
SRC-3 CC (%) 299 (92.8) 691 (89.0) 1   
rs6094752 CT (%) 20 (6.2) 80 (10.4) 0.58 0.35-0.96 0.033
C218R TT (%) 3 (1.0) 5 (0.6) 1.39 0.33-5.84 0.654
   [CT + TT]<-> [CC] 0.62 0.39-1.01 0.053
SRC-3 GG (%) 253 (78.1) 623 (79.4) 1   
rs2230782 GC (%) 68 (21.0) 150 (19.1) 1.12 0.81-1.54 0.502
Q586H CC (%) 3 (0.9) 12 (1.5) 0.62 0.17-2.20 0.451
   [CC]<-> [GG + GC] 0.60 0.16-2.14 0.429
SRC-3 AA (%) 270 (83.6) 653 (82.5) 1   
rs2076546 AG (%) 52 (16.1) 126 (15.9) 0.99 0.70-1.42 0.991
T960T GG (%) 1 (0.3) 12 (1.6) 0.20 0.02-1.56 0.088
   [AG + GG]<-> [AA] 0.93 0.66-1.31 0.676
SMRT GG (%) 222 (69.4) 517 (67.0) 1   
rs2229840 AG (%) 89 (27.8) 220 (28.5) 0.94 0.70-1.26 0.689
A1706T AA (%) 9 (2.8) 35 (4.5) 0.59 0.28-1.27 0.175
   [AG + GG]<-> [AA] 0.89 0.68-1.18 0.439
Cases and Controls < 50
SRC-1 CC (%) 682 (94.4) 685 (94.9) 1   
rs1804645 CT (%) 38 (5.3) 37 (5.1) 1.03 0.65-1.64 0.896
P1272S TT (%) 2 (0.3) 0 (0.0) - - -
   [CT + TT]<-> [CC] 1.08 0.69-1.72 0.725
SRC-3 CC (%) 633 (88.6) 639 (89.4) 1   
rs6094752 CT (%) 77 (10.8) 72 (10.1) 1.08 0.77-1.52 0.658
C218R TT (%) 4 (0.6) 4 (0.6) 1.01 0.25-4.05 0.989
   [CT + TT]<-> [CC] 1.08 0.77-1.50 0.665
SRC-3 GG (%) 592 (82.2) 584 (81.3) 1   
rs2230782 GC (%) 122 (16.9) 122 (17.0) 0.98 0.75-1.30 0.923
Q586H CC (%) 6 (0.9) 12 (1.7) 0.49 0.18-1.32 0.152
   [CC]<-> [GG + GC] 0.49 0.18-1.32 0.153
SRC-3 AA (%) 592 (82.1) 587 (81.7) 1   
rs2076546 AG (%) 123 (17.1) 123 (17.1) 0.99 0.75-1.30 0.952
T960T GG (%) 6 (0.8) 8 (1.2) 0.74 0.26-2.16 0.584
   [AG + GG]<-> [AA] 0.98 0.75-1.28 0.862
SMRT GG (%) 470 (66.9) 487 (68.4) 1   
rs2229840 AG (%) 202 (28.8) 203 (28.5) 1.03 0.82-1.30 0.796
A1706T AA (%) 30 (4.3) 22 (3.1) 1.41 0.80-2.48 0.228
   [AG + GG]<-> [AA] 1.07 0.85-1.33 0.561
  1. Odds ratios (OR) with 95% confidence intervals (95% CI) and P-values.