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Table 4 Multivariate analysis using Cox proportional hazards regression model for adjuvant chemotherapy treated Stage III patients.

From: APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling

Variable

HR

95% Confidence Interval

p value

Age

(>70 vs <70)

1.006

0.955-1.059

0.835

Gender

(Female vs Male)

0.532

0.159-1.783

0.307

Grade

(poor vs moderate vs well)

N/A

N/A

0.873

Site

(Proximal vs Distal)

5.015

0.695-36.191

0.110

APRIL

Tumour Stroma Staining

(positive vs negative)

6.250

1.471-26.316

0.013

APRIL

Tumour Cell Staining

(positive vs negative)

0.64

0.200-2.044

0.452