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Table 4 Multivariate analysis using Cox proportional hazards regression model for adjuvant chemotherapy treated Stage III patients.

From: APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling

Variable HR 95% Confidence Interval p value
Age (>70 vs <70) 1.006 0.955-1.059 0.835
Gender (Female vs Male) 0.532 0.159-1.783 0.307
Grade (poor vs moderate vs well) N/A N/A 0.873
Site (Proximal vs Distal) 5.015 0.695-36.191 0.110
APRIL Tumour Stroma Staining (positive vs negative) 6.250 1.471-26.316 0.013
APRIL Tumour Cell Staining (positive vs negative) 0.64 0.200-2.044 0.452