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Table 4 Multivariate analysis using Cox proportional hazards regression model for adjuvant chemotherapy treated Stage III patients.

From: APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling

Variable HR 95% Confidence Interval p value
Age
(>70 vs <70)
1.006 0.955-1.059 0.835
Gender
(Female vs Male)
0.532 0.159-1.783 0.307
Grade
(poor vs moderate vs well)
N/A N/A 0.873
Site
(Proximal vs Distal)
5.015 0.695-36.191 0.110
APRIL
Tumour Stroma Staining
(positive vs negative)
6.250 1.471-26.316 0.013
APRIL
Tumour Cell Staining
(positive vs negative)
0.64 0.200-2.044 0.452