Long term survival following the detection of circulating tumour cells in head and neck squamous cell carcinoma

BMC Cancer

Table 1 Disease characteristics of the 16 patients with head and neck cancers included in this study.

P#	Cancer Site	T	N	M	Stage	P	V	E	Margin	Diff
1	Rt Hypopharynx	1	2b	0	4a	n	n	n	involved	poor
2	Lt Tongue Base	2	1	0	3	n	Y	n	involved	mod
3	FOM	4	0	0	4a	Y	n	x	x	poor
4	RT Supraglottis	2	2b	0	4a	n	n	Y	clear	poor
5	Rt Tongue Base	1	2b	0	4a	n	n	Y	involved	mod
6	Rt Tongue Base	2	1	0	3	n	Y	n	clear	mod
7	Lt Hypopharynx	4	2c	0	4a	n	n	Y	5 mm	poor
8	Glottic	4	0	0	4a	x	n	x	clear	mod
9	Rt Lat Tongue	1	0	0	1	Y	n	x	10 mm	well
10	Lt Tonsil	3	2b	0	4a	n	n	Y	involved	poor
11	Rt Tonsil	2	2b	0	4a	n	n	Y	clear	mod
12	Glottic	3	0	0	3	x	n	x	15 mm	mod
13	Glottic	3	0	0	3	n	n	x	0 mm	mod
14	Transglottic	4	0	0	4a	x	Y	x	1 mm	Mod
15	Rt Lat Tongue	3	1	0	3	n	n	Y	3 mm	poor
16	Rt Lat Tongue	3	0	0	3	n	n	x	0.6 mm	well
P#	Recurrence	Radiation			Chemo	Outcome			Before	After
1	Distant	Y - 66 Gy in 32			n	Alive - metastatic disease			neg	POS
2	Local (tonsil)	Y - 64 Gy in 31			n	Died - disease			POS	neg
3	Local (tongue)	Y - 64 Gy in 32			n	Died - disease			POS	neg
4	Local (Node)	Y - 66 Gy in 32			n	Died - disease			POS	neg
5	Local	Y - 66 Gy in 33			n	Died - metastatic disease			POS	neg
6	n	n			n	Alive - Disease Free			POS	POS
7	Distant	Y - 66 Gy in 32			n	died - metastatic disease			POS	POS
8	n	Y - 66 Gy in 33			n	Alive - Disease Free			POS	POS
9	Distant	Y - 66 Gy in 34			n	died - metastatic disease			POS	POS
10	Distant	Y - 66 Gy in 35			Y	died - metastatic disease			neg	POS
11	n	Y - 66 Gy in 36			Y	Alive - Disease Free			POS	POS
12	n	n			n	died - other			neg	neg
13	Local	Y - 64 Gy in 31			Y	Alive - Disease Free			POS	POS
14	Local	Y - 64 Gy in 31			n	died - metastatic disease			neg	neg
15	Local	n			n	died - metastatic disease			POS	POS
16	n	n			n	Alive - Disease Free			neg	POS

P# denotes patient number. Information includes - Site of original cancer (cancer site); tumour size (T); nodal status (N); evidence of metastasis (M); evidence of perineural invasion (P); evidence of vascular invasion (V); evidence of extracapsular invasion (E); whether the margin was involved with tumour after surgery or clear; differentiation of the tumour (Diff); Site of recurrence (Recurrence); whether (Y), or not (n), radiation was given post-surgery (Radiation) including dosage - Grays (Gy) in fractions; whether (Y), or not (n), chemotherapy was given (Chemo); the outcome at last follow-up (Outcome); and whether the patients were positive (POS) or negative (neg), before and after surgery for at least 2 of the RT-PCR markers. Y denotes yes, n denotes no, x denotes unknown.

ISSN: 1471-2407