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Figure 3 | BMC Cancer

Figure 3

From: Identification of colorectal cancer patients with tumors carrying the TP53mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy

Figure 3

Effect of chemotherapy and the TP53 mutation on codon 72 polymorphic allele in Dukes' stage C patients. (a): Overall survival of a Dukes' stage C and chemotherapy patient with the TP53 mutation of the Arg allele and Pro allele (n = 35, P = 0.368). (b): Overall survival of patients without chemotherapy and with TP53 mutation of the Arg and Pro allele (n = 16, P = 0.012). Dukes' stage C patients with TP53 mutation on the Pro allele show a significant effect of chemotherapy (c) (n = 18, P = 0.012), but the patients with mutation on the Arg allele did not reach statistical significance (d)(n = 33, P = 0.112).

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BMC Cancer

ISSN: 1471-2407

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